Brookstreet at HBS Alumni Event with Moderna CEO Stephane Bancel

Partners at Brookstreet who are alumni of Harvard Business School joined the HBS-Alumni "Moderna" Case Discussion with CEO Stéphane Bancel (HBS MBA 2000, AMP 170) and HBS Professor Karim Lakhani.

If one asks what does a fund dealing with ESG, TECH and SAAS can learn from a biotech firm, please read below.

Moderna started out as project LS18 in 2010 at Cambridge-based Flagship, at the time called Flagship Ventures.

To understand the genesis of Moderna, one must understand Flagship…

Flagship followed a structured four-stage process for pioneering innovations through scientific discovery.

  • First, they generated hypotheses believed to yield break-through innovations, asking thequestion “What if?” (e.g., “What if mRNA could be a drug?”). They called these “explorations”.

  • Second, if these explorations proved promising, they became prototype companies (ProtoCos). Flagship formed to test the feasibility of the concept.

  • Third, if the explorations validated the science underlying the venture, ProtoCos turned into new companies (NewCos) and Flagship committed significant capital.

  • Fourth, the NewCo was spun out to become a growth company (GrowthCo). 

Moderna is a digital biotech firm where they paid attention to i) the Cloud, ii) integration iii) automation and robotics iv) AI-interconnectivity and big data.

Just to understand what it means to digitise and SPEED process.  

  • On January 11, the Covid 19 gene sequencing data was posted on Virological.org

  • Two days later, January 13, Moderna team finalized the design of a corona vaccine candidate.

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